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E3 ligase Ligand-Linker Conjugate 32

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Click Chemistry

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-126458

    E3 ligase Ligand-Linker Conjugates 32

    E3 Ligase Ligand-Linker Conjugates Autophagy Apoptosis Cancer
    Thalidomide-O-PEG2-propargyl (E3 ligase Ligand-Linker Conjugates 32) is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and 2-unit PEG linker used in PROTAC technology . Thalidomide-O-PEG2-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Thalidomide-O-PEG2-propargyl
  • HY-157590

    Ligands for E3 Ligase Cancer
    E3 ligase Ligand-Linker Conjugate 32 is a conjugate of E3 ligase ligand and linker, consisting of (S,R,S)-AHPC (HY-125845) and the corresponding Linker. (S,R,S)-AHPC is a VH032-based von Hippel-Lindau (VHL) ligand that recruits VHL proteins. E3 ligase Ligand-Linker Conjugate 32 can be used as a key intermediate for the synthesis of complete PROTAC molecules.
    <em>E3</em> <em>ligase</em> <em>Ligand-Linker</em> <em>Conjugate 32</em>

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